Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. It appears mostly in young patients and females, the maxillary.

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This page was last edited on 26 Juneat Dreibaldt in was the first to describe adenomatoid odontogenic tumor AOTwhich is an uncommon benign epithelial lesion of odontogenic origin known as a pseudo-adenoameloblastoma [ 1 ]. InAOT was described as pseudo-adenoameloblastoma by Dreibladt. The adenomatoid odontogenic tumor. The origin of AOT is controversial, but many author believe in odontogenic source.

Case Report A year-old female consulted with a chief complaint of an asymptomatic swelling mass persistent from approximately 12 months on the left maxillary anterior region which increased gradually and achieved the present size of 1. The lumen may be empty or contain amorphous eosinophilic material. This article has been cited by other articles in PMC. The history revealed an orthodontic treatment started in December with a treatment plan involving extraction of teeth 34, 44, 23, and It is mostly seen in young patients with a greater predilection for females.

However, an AOT often appears to envelop the crown as well, where we divided the specimen to show the relation of the lesion to the tooth, unlike the dentigerous cyst which does not surround the roots [ 131416 ]. Adenomatoid odontogenic tumor arising from the mandibular molar region: The latter did not express laminin and apparently was prone to mineralization, and probably corresponded to the material positive to enamel protein in the study of Takata, et al.


The former was immunohistochemically positive for laminin, therefore, representing substance of the basal membrane. Odontogenic neoplasms; Adenomatoid odontogenic tumor; Immunohistochemistry.

Philipsen and Reichart 14 considered AOT a non-invasive slow-growing benign lesion hamartomatous.

Adenomatoid odontogenic tumor, an uncommon tumor

We could accept the rare formation of adenomwtoid next to the AOT, but as secondary phenomenon in the tumor pathogenesis. Oral and Maxillofacial Pathology. The axial slides of CBCT Figure 3 showed a well-circumscribed radiolucent lesion with well-defined radiopaque border extending horizontally from maxillary midline to the distal margin of the second premolar and vertically from the nasal base to the midpart of the roots of teeth 21 and J Oral Maxillofac Surg.

It should be differentially diagnosed from a dentigerous cyst and the main difference is that the radiolucency in case of AOT extends apically beyond the cementoenamel junction.

AOT usually occurs within the tooth bearing areas of jaws and often found in association with impacted teeth. From Wikipedia, the free encyclopedia.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation

How to cite this article: Peripheral extraosseous forms of the tumor are also encountered tumog are rare [ 389 ]. Immunohistochemical demonstration of an enamel sheath protein, sheatlin, odontoegnic odontogenic tumors. The large adenomatoid structures, resulting from the circular tridimensional, “tubular” configuration of the columnar cells and cylindrical superficial cells of the REE due to its hamartomatous growth, would be formed in recent tumors, right from their onset.


Komal K, Vibhakar A. In Philipson and Birn proposed the name adenomatoid odontogenic tumor. There are three variants of AOT: Anteroposteriorly, it extended from the mesial margin of the first premolar up to the distal margin of the odontobenic premolar.

This material may stain for amyloid [ adebomatoidsdenomatoid ]. J Oral Pathol Med ; There are flakes of radio-opaque areas inside the lesion. In the World Health Organization classification of odontogenic tumors established inAOT was mentioned [ 14 ] as a mixed odontogenic neoplasm, in other words, an epithelial tumor with an inductive effect on the odontogenic mesenchyme [ 15 ].

The distinction between these two substances in the routine hematoxylin and eosin staining is possible. Mostly, AOTs are the central follicular type and appear as well-demarcated radiolucent lesions. It is the fourth most common odontogenic tumor which is benign, slowly growing and has three variants, follicular, extrafollicular, and peripheral.

We had an interesting CK14 immunohistochemical adwnomatoid. Case Report A year-old female child reported to our clinic with a complaint of missing teeth in the right maxilla with a medical history taking epileptic drugs.